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HJURP Antikörper (AA 13-574)

Dieses Anti-HJURP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HJURP in WB, ELISA und FACS. Geeignet für Maus und Ratte.
Produktnummer ABIN7599943

Kurzübersicht für HJURP Antikörper (AA 13-574) (ABIN7599943)

Target

Alle HJURP Antikörper anzeigen
HJURP (Holliday Junction Recognition Protein (HJURP))

Reaktivität

Maus, Ratte

Wirt

  • 25
Kaninchen

Klonalität

  • 24
  • 1
Polyklonal

Konjugat

  • 15
  • 3
  • 2
  • 2
  • 2
  • 1
Dieser HJURP Antikörper ist unkonjugiert

Applikation

  • 21
  • 15
  • 10
  • 10
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 13-574

    Verwendungszweck

    Anti-Hjurp Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Hjurp Antibody Picoband® (ABIN7599943). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived mouse Hjurp recombinant protein (Position: Q13-T574).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/16/2009. 2. Kato, T., Sato, N., Hayama, S., Yamabuki, T., Ito, T., Miyamoto, M., Kondo, S., Nakamura, Y., Daigo, Y. Activation of Holliday junction-recognizing protein involved in the chromosomal stability and immortality of cancer cells. Cancer Res. 67: 8544-8553, 2007. 3. Nardi, I. K., Zasadzinska, E., Stellfox, M. E., Knippler, C. M., Foltz, D. R. Licensing of centromeric chromatin assembly through the Mis18-alpha-Mis18-beta heterotetramer. Molec. Cell 61: 774-787, 2016.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    HJURP (Holliday Junction Recognition Protein (HJURP))

    Andere Bezeichnung

    Hjurp

    Hintergrund

    Synonyms: AF4/FMR2 family member 4,ALL1-fused gene from chromosome 5q31 protein,Protein AF-5q31,Major CDK9 elongation factor-associated protein,AFF4,AF5Q31, MCEF,HSPC092,

    Tissue Specificity: Ubiquitously expressed. Strongly expressed in heart, placenta, skeletal muscle, pancreas and to a lower extent in brain. .

    Background: Holliday junction recognition protein is a protein in humans that is encoded by the HJURP gene. HJURP (holliday junction recognition protein) is a protein coding gene. Diseases associated with HJURP include fibrillary astrocytoma. Among its related pathways are DNA damage and chromosome maintenance. Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. ly binds holliday junctions.

    Molekulargewicht

    84 kDa

    Gen-ID

    381280
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