ABRA Antikörper (AA 13-381)

Produktnummer ABIN7599939

Der Kaninchen Polyklonal Anti-ABRA-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ABRA in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ABRA Antikörper (AA 13-381) (ABIN7599939)

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ABRA Antikörper

Bindungsspezifität: AA 13-381

Verwendungszweck: Anti-ABRA Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-ABRA Antibody Picoband® (ABIN7599939). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ABRA recombinant protein (Position: A13-K381).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Arai, A., Spencer, J. A., Olson, E. N. STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription. J. Biol. Chem. 277: 24453-24459, 2002. 2. Kuwahara, K., Barrientos, T., Pipes, G. C. T., Li, S., Olson, E. N. Muscle-specific signaling mechanism that links actin dynamics to serum response factors. Molec. Cell. Biol. 25: 3173-3181, 2005. 3. Kuwahara, K., Teg Pipes, G. C., McAnally, J., Richardson, J. A., Hill, J. A., Bassel-Duby, R., Olson, E. N. Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity. J. Clin. Invest. 117: 1324-1334, 2007.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu ABRA

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Andere Bezeichnung: ABRA

Hintergrund:

Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Background: Predicted to enable actin binding activity. Predicted to be involved in positive regulation of DNA-binding transcription factor activity, positive regulation of Rho protein signal transduction, and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of transcription, DNA-templated and protein import into nucleus. Located in plasma membrane.

Molekulargewicht: 39 kDa

Gen-ID: 137735

UniProt: Q8N0Z2

Pathways: Protein targeting to Nucleus