PATL2 Antikörper (AA 123-411)

Produktnummer ABIN7599862

Dieses Anti-PATL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PATL2 in WB, IF, ELISA, ICC und FACS. Geeignet für Maus, Ratte und Human.

Kurzübersicht für PATL2 Antikörper (AA 123-411) (ABIN7599862)

Target: PATL2 (Protein Associated with Topoisomerase II Homolog 2 (PATL2))

Reaktivität: Maus, Ratte, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PATL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-PATL2 Antikörper

Bindungsspezifität: AA 123-411

Verwendungszweck: Anti-PATL2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PATL2 Antibody Picoband® (ABIN7599862). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PATL2 recombinant protein (Position: Q123-Q411).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, B., Zhang, Z., Sun, X., Kuang, Y., Mao, X., Wang, X., Yan, Z., Li, B., Xu, Y., Yu, M., Fu, J., Mu, J., Zhou, Z., Li, Q., Jin, L., He, L., Sang, Q., Wang, L. Biallelic mutations in PATL2 cause female infertility characterized by oocyte maturation arrest. Am. J. Hum. Genet. 101: 609-615, 2017. 2. Maddirevula, S., Coskun, S., Alhassan, S., Elnour, A., Alsaif, H. S., Ibrahim, N., Abdulwahab, F., Arold, S. T., Alkuraya, F. S. Female infertility caused by mutations in the oocyte-specific translational repressor PATL2. Am. J. Hum. Genet. 101: 603-608, 2017. 3. Scheller, N., Resa-Infante, P., de la Luna, S., Galao, R. P., Albrecht, M., Kaestner, L., Lipp, P., Lengauer, T., Meyerhans, A., Diez, J. Identification of PatL1, a human homolog to yeast P body component Pat1. Biochim. Biophys. Acta 1773: 1786-1792, 2007.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PATL2

Target: PATL2 (Protein Associated with Topoisomerase II Homolog 2 (PATL2))

Andere Bezeichnung: PATL2

Hintergrund:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in cytoplasm.

Molekulargewicht: 59 kDa

Gen-ID: 197135