NAB1 Antikörper (AA 120-480)

Produktnummer ABIN7599831

Der Kaninchen Polyklonal Anti-NAB1-Antikörper wurde für WB, ICC, IF und ELISA validiert. Er ist geeignet, NAB1 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für NAB1 Antikörper (AA 120-480) (ABIN7599831)

Target: NAB1 (NGFI-A Binding Protein 1 (EGR1 Binding Protein 1) (NAB1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA

Produktdetails anti-NAB1 Antikörper

Bindungsspezifität: AA 120-480

Verwendungszweck: Anti-NAB1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-NAB1 Antibody Picoband® (ABIN7599831). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NAB1 recombinant protein (Position: A120-K480).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Buitrago, M., Lorenz, K., Maass, A. H., Oberdorf-Maass, S., Keller, U., Shmitteckert, E. M., Ivashchenko, Y., Lohse, M. J., Engelhardt, S. The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy. Nature Med. 11: 837-844, 2005. 2. Le, N., Nagarajan, R., Wang, J. Y. T., Svaren, J., LaPash, C., Araki, T., Schmidt, R. E., Milbrandt, J. Nab proteins are essential for peripheral nervous system myelination. Nature Neurosci. 8: 932-940, 2005. 3. Russo, M. W., Sevetson, B. R., Milbrandt, J. Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription. Proc. Nat. Acad. Sci. 92: 6873-6877, 1995.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NAB1

Target: NAB1 (NGFI-A Binding Protein 1 (EGR1 Binding Protein 1) (NAB1))

Andere Bezeichnung: NAB1

Hintergrund:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, USP21, USP23, PP1490

Tissue Specificity: Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.

Background: NGFI-A-binding protein 1 is a protein that in humans is encoded by the NAB1 gene. Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to act upstream of or within endochondral ossification, nervous system development, and regulation of epidermis development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus.

Molekulargewicht: 56 kDa

Gen-ID: 4664

UniProt: Q13506