ANKRD1 Antikörper (AA 120-319)

Produktnummer ABIN7599829

Dieses Anti-ANKRD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ANKRD1 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ANKRD1 Antikörper (AA 120-319) (ABIN7599829)

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ANKRD1 Antikörper

Bindungsspezifität: AA 120-319

Verwendungszweck: Anti-ANKRD1 Antibody Picoband®

Produktmerkmale: Anti-ANKRD1 Antibody Picoband® (ABIN7599829). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ANKRD1 recombinant protein (Position: D120-F319). Human ANKRD1 shares 93.5% and 95% amino acid (aa) sequence identity with mouse and rat ANKRD1, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Chu, W., Burns, D. K., Swerlick, R. A., Presky, D. H. Identification and characterization of a novel cytokine-inducible nuclear protein from human endothelial cells. J. Biol. Chem. 270: 10236-10245, 1995. 2. de Waard, V., van Achterberg, T. A. E., Beauchamp, N. J., Pannekoek, H., de Vries, C. J. M. Cardiac ankyrin repeat protein (CARP) expression in human and murine atherosclerotic lesions: activin induces Carp in smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 23: 64-68, 2003. 3. Kanai, H., Tanaka, T., Aihara, Y., Takeda, S., Kawabata, M., Miyazono, K., Nagai, R., Kurabayashi, M. Transforming growth factor-beta/Smads signaling induces transcription of the cell type-restricted ankyrin repeat protein CARP gene through CAGA motif in vascular smooth muscle cells. Circ. Res. 88: 30-36, 2001.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu ANKRD1

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Andere Bezeichnung: ANKRD1

Hintergrund: Ankyrin repeat domain-containing protein 1, or Cardiac ankyrin repeat protein is a protein that in humans is encoded by the ANKRD1 gene also known as CARP. The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.

Molekulargewicht: 36 kDa

Gen-ID: 27063

UniProt: Q15327

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Response to DNA Damage Stimulus