TOMM40 Antikörper (AA 111-315)

Produktnummer ABIN7599738

Dieses Anti-TOMM40-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TOMM40 in WB, ELISA, IHC, IF, FACS und ICC. Geeignet für Human.

Kurzübersicht für TOMM40 Antikörper (AA 111-315) (ABIN7599738)

Target: TOMM40 (Translocase of Outer Mitochondrial Membrane 40 Homolog (TOMM40))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOMM40 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-TOMM40 Antikörper

Bindungsspezifität: AA 111-315

Verwendungszweck: Anti-TOMM40 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TOMM40 Antibody Picoband® (ABIN7599738). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TOMM40 recombinant protein (Position: N111-K315).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Freitas, E. M., Zhang, W. J., Lalonde, J.-P., Tay, G. K., Gaudieri, S., Ashworth, L. K., van Bockxmeer, F. M., Dawkins, R. L. Sequencing of 42kb of the APO E-C2 gene cluster reveals a new gene: PEREC1. DNA Seq. 9: 89-101, 1998. 2. Gabriel, K., Egan, B., Lithgow, T. Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins. EMBO J. 22: 2380-2386, 2003. 3. Humphries, A. D., Streimann, I. C., Stojanovski, D., Johnston, A. J., Yano, M., Hoogenraad, N. J., Ryan, M. T. Dissection of the mitochondrial import and assembly pathway for human Tom40. J. Biol. Chem. 280: 11535-11543, 2005.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TOMM40

Target: TOMM40 (Translocase of Outer Mitochondrial Membrane 40 Homolog (TOMM40))

Andere Bezeichnung: TOMM40

Hintergrund:

Synonyms: IFNGR2 protein, Interferon gamma receptor 2, IFNGR2, mCG_11456

Tissue Specificity: Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Background: Translocase of outer mitochondrial membrane 40 homolog (yeast), also known as TOMM40, is a protein which in humans is encoded by the TOMM40 gene. The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 38 kDa

Gen-ID: 10452

UniProt: O96008