ACAD9 Antikörper (AA 110-595)

Produktnummer ABIN7599735

Dieses Anti-ACAD9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ACAD9 in ELISA und WB. Geeignet für Human und Affe.

Kurzübersicht für ACAD9 Antikörper (AA 110-595) (ABIN7599735)

Target: ACAD9 (Acyl-CoA Dehydrogenase Family, Member 9 (ACAD9))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACAD9 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-ACAD9 Antikörper

Bindungsspezifität: AA 110-595

Verwendungszweck: Anti-ACAD9 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-ACAD9 Antibody Picoband® (ABIN7599735). Tested in ELISA, WB applications. This antibody reacts with Human, monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ACAD9 recombinant protein (Position: Q110-D595).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Monkey
ELISA, 0.1-0.5 μg/mL, -
1. Dewulf, J. P., Barrea, C., Vincent, M.-F., De Laet, C., Van Coster, R., Seneca, S., Marie, S., Nassogne, M.-C. Evidence of a wide spectrum of cardiac involvement due to ACAD9 mutations: report on nine patients. Molec. Genet. Metab. 118: 185-189, 2016. 2. Ensenauer, R., He, M., Willard, J.-M., Goetzman, E. S., Corydon, T. J., Vandahl, B. B., Mohsen, A.-W., Isaya, G., Vockley, J. Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids. J. Biol. Chem. 280: 32309-32316, 2005. 3. Haack, T. B., Danhauser, K., Haberberger, B., Hoser, J., Strecker, V., Boehm, D., Uziel, G., Lamantea, E., Invernizzi, F., Poulton, J., Rolinski, B., Iuso, A., Biskup, S., Schmidt, T., Mewes, H.-W., Wittig, I., Meitinger, T., Zeviani, M., Prokisch, H. Exome sequencing identifies ACAD9 mutations as a cause of complex I deficiency. Nature Genet. 42: 1131-1134, 2010.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu ACAD9

Target: ACAD9 (Acyl-CoA Dehydrogenase Family, Member 9 (ACAD9))

Andere Bezeichnung: ACAD9

Hintergrund:

Synonyms: Histone deacetylase 10, HD10, HDAC10

Tissue Specificity: Ubiquitous. High expression in liver, spleen, pancreas and kidney.

Background: Acyl-CoA dehydrogenase family member 9, mitochondrial is an enzyme that in humans is encoded by the ACAD9 gene. This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 65 kDa

Gen-ID: 28976

UniProt: Q9H845

Pathways: SARS-CoV-2 Protein Interaktom