Rab4 Antikörper (AA 110-216)

Produktnummer ABIN7599733

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Rab4 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Rab4 Antikörper (AA 110-216) (ABIN7599733)

Target: Rab4 (RAB4A) (RAB4A, Member RAS Oncogene Family (RAB4A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rab4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Rab4 Antikörper

Bindungsspezifität: AA 110-216

Verwendungszweck: Anti-Rab4/RAB4A Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Rab4/RAB4A Antibody Picoband® (ABIN7599733). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Rab4/RAB4A recombinant protein (Position: D110-C216).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Barbosa, M. D. F. S., Johnson, S. A., Achey, K., Gutierrez, M., Wakeland, E. K., Zerial, M., Kingsmore, S. F. The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics 30: 439-444, 1995. 2. Bielli, A., Thornqvist, P.-O., Hendrick, A. G., Finn, R., Fitzgerald, K., McCaffrey, M. W. The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate chain-1. Biochem. Biophys. Res. Commun. 281: 1141-1153, 2001. 3. Goueli, B. S., Powell, M. B., Finger, E. C., Pfeffer, S. R. TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling. Proc. Nat. Acad. Sci. 109: 15787-15792, 2012.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Rab4

Target: Rab4 (RAB4A) (RAB4A, Member RAS Oncogene Family (RAB4A))

Andere Bezeichnung: RAB4A

Hintergrund:

Synonyms: Solute carrier family 12 member 5, Electroneutral potassium-chloride cotransporter 2, K-Cl cotransporter 2, hKCC2, Neuronal K-Cl cotransporter, SLC12A5, KCC2, KIAA1176

Tissue Specificity: Brain specific. Detected in neuronal cells.

Background: This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.

Molekulargewicht: 24 kDa

Gen-ID: 5867

UniProt: P20338