RERE Antikörper (AA 109-1037)

Produktnummer ABIN7599696

Dieses Anti-RERE-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RERE in WB, ELISA, IHC, FACS, IF und ICC. Geeignet für Human.

Kurzübersicht für RERE Antikörper (AA 109-1037) (ABIN7599696)

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RERE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-RERE Antikörper

Bindungsspezifität: AA 109-1037

Verwendungszweck: Anti-RERE Antibody Picoband®

Produktmerkmale: Anti-RERE Antibody Picoband® (ABIN7599696). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RERE recombinant protein (Position: D109-H1037). Human RERE shares 92.4% and 92.3% amino acid (aa) sequence identity with mouse and rat RERE, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Amler, L. C., Bauer, A., Corvi, R., Dihlmann, S., Praml, C., Cavenee, W. K., Schwab, M., Hampton, G. M. Identification and characterization of novel genes located at the t(1,15)(p36.2,q24) translocation breakpoint in the neuroblastoma cell line NGP. Genomics 64: 195-202, 2000. 2. Bosch, D. G. M., Boonstra, F. N., de Leeuw, N., Pfundt, R., Nillesen, W. M., de Ligt, J., Gilissen, C., Jhangiani, S., Lupski, J. R., Cremers, F. P. M., de Vries, B. B. A. Novel genetic causes for cerebral visual impairment. Europ. J. Hum. Genet. 24: 660-665, 2016. 3. Fregeau, B., Kim, B. J., Hernandez-Garcia, A., Jordan, V. K., Cho, M. T., Schnur, R. E., Monaghan, K. G., Juusola, J., Rosenfeld, J. A., Bhoj, E., Zackai, E. H., Sacharow, S., and 14 others. De novo mutations of RERE cause a genetic syndrome with features that overlap those associated with proximal 1p36 deletions. Am. J. Hum. Genet. 98: 963-970, 2016.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu RERE

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Andere Bezeichnung: RERE

Hintergrund: Arginine-glutamic acid dipeptide repeats protein is a protein that in humans is encoded by the RERE gene. This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 170,212 kDa

Gen-ID: 473

UniProt: Q9P2R6

Pathways: Protein targeting to Nucleus