Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

KIF1A Antikörper (AA 1079-1628)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KIF1A in ELISA, WB und FACS. Er zeigt eine Reaktivität gegenüber Maus, Human und Ratte.
Produktnummer ABIN7599679

Kurzübersicht für KIF1A Antikörper (AA 1079-1628) (ABIN7599679)

Target

Alle KIF1A Antikörper anzeigen
KIF1A (Kinesin Family Member 1A (KIF1A))

Reaktivität

  • 10
  • 8
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Maus, Human, Ratte

Wirt

  • 11
  • 3
Kaninchen

Klonalität

  • 11
  • 3
Polyklonal

Konjugat

  • 10
  • 2
  • 1
  • 1
Dieser KIF1A Antikörper ist unkonjugiert

Applikation

  • 9
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 5
    • 2
    • 1
    • 1
    AA 1079-1628

    Verwendungszweck

    Anti-KIF1A Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-KIF1A Antibody Picoband® (ABIN7599679). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human KIF1A recombinant protein (Position: H1079-Y1628).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chiba, K., Takahashi, H., Chen, M., Obinata, H., Arai, S., Hashimoto, K., Oda, T., McKenney, R. J., Niwa, S. Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors. Proc. Nat. Acad. Sci. 116: 18429-18434, 2019. 2. Citterio, A., Arnoldi, A., Panzeri, E., Merlini, L., D'Angelo, M. G., Musumeci, O., Toscano, A., Bondi, A., Martinuzzi, A., Bresolin, N., Bassi, M. T. Variants in KIF1A gene in dominant and sporadic forms of hereditary spastic paraparesis. J. Neurol. 262: 2684-2690, 2015. 3. Erlich, Y., Edvardson, S., Hodges, E., Zenvirt, S., Thekkat, P., Shaag, A., Dor, T., Hannon, G. J., Elpeleg, O. Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis. Genome Res. 21: 658-664, 2011.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    KIF1A (Kinesin Family Member 1A (KIF1A))

    Andere Bezeichnung

    KIF1A

    Hintergrund

    Synonyms: S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin, SAG,

    Tissue Specificity: Retina and pineal gland.

    Background: Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded by the KIF1A gene. The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    Molekulargewicht

    191 kDa

    Gen-ID

    547

    UniProt

    Q12756
Sie sind hier:
Chat with us!