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KIF1A Antikörper (AA 1079-1628)

KIF1A Reaktivität: Maus, Human, Ratte ELISA, WB, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7599679
  • Target Alle KIF1A Antikörper anzeigen
    KIF1A (Kinesin Family Member 1A (KIF1A))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    AA 1079-1628
    Reaktivität
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Human, Ratte
    Wirt
    • 11
    • 3
    Kaninchen
    Klonalität
    • 11
    • 3
    Polyklonal
    Konjugat
    • 10
    • 2
    • 1
    • 1
    Dieser KIF1A Antikörper ist unkonjugiert
    Applikation
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    Verwendungszweck
    Anti-KIF1A Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-KIF1A Antibody Picoband® (ABIN7599679). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human KIF1A recombinant protein (Position: H1079-Y1628).
    Isotyp
    IgG
    Top Product
    Discover our top product KIF1A Primärantikörper
  • Applikationshinweise
    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chiba, K., Takahashi, H., Chen, M., Obinata, H., Arai, S., Hashimoto, K., Oda, T., McKenney, R. J., Niwa, S. Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors. Proc. Nat. Acad. Sci. 116: 18429-18434, 2019. 2. Citterio, A., Arnoldi, A., Panzeri, E., Merlini, L., D'Angelo, M. G., Musumeci, O., Toscano, A., Bondi, A., Martinuzzi, A., Bresolin, N., Bassi, M. T. Variants in KIF1A gene in dominant and sporadic forms of hereditary spastic paraparesis. J. Neurol. 262: 2684-2690, 2015. 3. Erlich, Y., Edvardson, S., Hodges, E., Zenvirt, S., Thekkat, P., Shaag, A., Dor, T., Hannon, G. J., Elpeleg, O. Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis. Genome Res. 21: 658-664, 2011.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    KIF1A (Kinesin Family Member 1A (KIF1A))
    Andere Bezeichnung
    KIF1A (KIF1A Produkte)
    Hintergrund

    Synonyms: S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin, SAG,

    Tissue Specificity: Retina and pineal gland.

    Background: Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded by the KIF1A gene. The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    Molekulargewicht
    191 kDa
    Gen-ID
    547
    UniProt
    Q12756
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