GATA6 Antikörper (AA 105-151)

Produktnummer ABIN7599662

Der Kaninchen Polyklonal Anti-GATA6-Antikörper wurde für ELISA, WB, IF, ICC und FACS validiert. Er ist geeignet, GATA6 in Proben von Human zu detektieren.

Kurzübersicht für GATA6 Antikörper (AA 105-151) (ABIN7599662)

Target: GATA6 (GATA Binding Protein 6 (GATA6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-GATA6 Antikörper

Bindungsspezifität: AA 105-151

Verwendungszweck: Anti-GATA6 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-GATA6 Antibody Picoband® (ABIN7599662). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GATA6 recombinant protein (Position: N105-L151).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ho, C. K. M., Wood, J. R., Stewart, D. R., Ewens, K., Ankener, W., Wickenheisser, J., Nelson-Degrave, V., Zhang, Z., Legro, R. S., Dunaif, A., McAllister, J. M., Spielman, R., Strauss, J. F., III. Increased transcription and increased messenger ribonucleic acid (mRNA) stability contribute to increased GATA6 mRNA abundance in polycystic ovary syndrome theca cells. J. Clin. Endocr. Metab. 90: 6596-6602, 2005. 2. Kamnasaran, D., Qian, B., Hawkins, C., Stanford, W. L., Guha, A. GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model. Proc. Nat. Acad. Sci. 104: 8053-8058, 2007. 3. Ketola, I., Toppari, J., Vaskivuo, T., Herva, R., Tapanainen, J. S., Heikinheimo, M. Transcription factor GATA-6, cell proliferation, apoptosis, and apoptosis-related proteins Bcl-2 and Bax in human fetal testis. J. Clin. Endocr. Metab. 88: 1858-1865, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu GATA6

Target: GATA6 (GATA Binding Protein 6 (GATA6))

Andere Bezeichnung: GATA6

Hintergrund:

Synonyms: RNA-binding protein FUS, 75 kDa DNA-pairing protein, Oncogene FUS, Oncogene TLS, POMp75, Translocated in liposarcoma protein, FUS, TLS,

Tissue Specificity: Ubiquitous.

Background: Transcription factor GATA-6, also known as GATA-binding factor 6 (GATA6), is protein that in humans is encoded by the GATA6 gene. This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects.

Molekulargewicht: 65 kDa

Gen-ID: 2627

UniProt: Q92908