Syntaxin 12 Antikörper (AA 103-245)

Produktnummer ABIN7599647

Der Kaninchen Polyklonal Anti-Syntaxin 12-Antikörper wurde für WB, ELISA, IF, FACS und ICC validiert. Er ist geeignet, Syntaxin 12 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Syntaxin 12 Antikörper (AA 103-245) (ABIN7599647)

Target: Syntaxin 12 (STX12)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syntaxin 12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-Syntaxin 12 Antikörper

Bindungsspezifität: AA 103-245

Verwendungszweck: Anti-Syntaxin 12/STX12 Antibody Picoband®

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Anti-Syntaxin 12/STX12 Antibody Picoband® (ABIN7600936). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Syntaxin 12/STX12 recombinant protein (Position: K103-K245). Human STX12 shares 95.1% and 93.7% amino acid (aa) sequence identity with mouse and rat STX12, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Advani, R. J., Bae, H.-R., Bock, J. B., Chao, D. S., Doung, Y.-C., Prekeris, R., Yoo, J.-S., Scheller, R. H. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. J. Biol. Chem. 273: 10317-10324, 1998. 2. Ambrosio, A. L., Febvre, H. P., Di Pietro, S. M. Syntaxin 12 and COMMD3 are new factors that function with VPS33B in the biogenesis of platelet alpha-granules. Blood 139: 922-935, 2022. 3. Collins, R. F., Schreiber, A. D., Grinstein, S., Trimble, W. S. Syntaxins 13 and 7 function at distinct steps during phagocytosis. J. Immun. 169: 3250-3256, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Syntaxin 12

Target: Syntaxin 12 (STX12)

Andere Bezeichnung: STX12

Hintergrund:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: Syntaxin-12 is a protein that in humans is encoded by the STX12 gene. STX12 functions with the VPS16B/VPS33B (608552) complex in the biogenesis of platelet alpha-granules.

Molekulargewicht: 37 kDa

Gen-ID: 23673

UniProt: Q86Y82

Pathways: Synaptic Vesicle Exocytosis