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Ninein Antikörper (AA 1023-2090)

Dieses Anti-Ninein-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ninein in WB, ELISA und FACS. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7599645

Kurzübersicht für Ninein Antikörper (AA 1023-2090) (ABIN7599645)

Target

Alle Ninein (NIN) Antikörper anzeigen
Ninein (NIN) (Ninein (GSK3B Interacting Protein) (NIN))

Reaktivität

Human, Maus, Ratte

Wirt

  • 16
Kaninchen

Klonalität

  • 16
Polyklonal

Konjugat

  • 12
  • 2
  • 1
  • 1
Dieser Ninein Antikörper ist unkonjugiert

Applikation

  • 11
  • 9
  • 8
  • 7
  • 5
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 1023-2090

    Verwendungszweck

    Anti-Ninein/NIN Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Ninein/NIN Antibody Picoband® (ABIN7599645). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Ninein/NIN recombinant protein (Position: Q1023-H2090).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chen, C.-H., Howng, S.-L., Cheng, T.-S., Chou, M.-H., Huang, C.-Y., Hong, Y.-R. Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle. Biochem. Biophys. Res. Commun. 308: 975-983, 2003. 2. Chou, C. H., Loh, J. K., Yang, M. C., Lin, C. C., Hong, M. C., Cho, C. L., Chou, A. K., Wang, C. H., Lieu, A. S., Howng, S. L., Hsu, C. M., Hong, Y. R. AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1. Cell Cycle 14: 2764-2776, 2015. 3. Dauber, A., LaFranchi, S. H., Maliga, Z., Lui, J. C., Moon, J. E., McDeed, C., Henke, K., Zonana, J., Kingman, G. A., Pers, T. H., Baron, J., Rosenfeld, R. G., Hirschhorn, J. N., Harris, M. P., Hwa, V. Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein. J. Clin. Endocr. Metab. 97: E2140-E2151, 2012. Note: Electronic Article.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    Ninein (NIN) (Ninein (GSK3B Interacting Protein) (NIN))

    Andere Bezeichnung

    NIN

    Hintergrund

    Synonyms: Endoglin, Cell surface MJ7/18 antigen, CD105, Eng, Edg,

    Background: Ninein is a protein that in humans is encoded by the NIN gene. This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.

    Molekulargewicht

    260 kDa

    Gen-ID

    51199

    UniProt

    Q8N4C6

    Pathways

    Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom
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