Ninein Antikörper (AA 1023-2090)

Produktnummer ABIN7599645

Produktdetails anti-Ninein Antikörper

Target: Ninein (NIN) (Ninein (GSK3B Interacting Protein) (NIN))

Bindungsspezifität: AA 1023-2090

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ninein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Verwendungszweck: Anti-Ninein/NIN Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Ninein/NIN Antibody Picoband® (ABIN7599645). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Ninein/NIN recombinant protein (Position: Q1023-H2090).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, C.-H., Howng, S.-L., Cheng, T.-S., Chou, M.-H., Huang, C.-Y., Hong, Y.-R. Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle. Biochem. Biophys. Res. Commun. 308: 975-983, 2003. 2. Chou, C. H., Loh, J. K., Yang, M. C., Lin, C. C., Hong, M. C., Cho, C. L., Chou, A. K., Wang, C. H., Lieu, A. S., Howng, S. L., Hsu, C. M., Hong, Y. R. AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1. Cell Cycle 14: 2764-2776, 2015. 3. Dauber, A., LaFranchi, S. H., Maliga, Z., Lui, J. C., Moon, J. E., McDeed, C., Henke, K., Zonana, J., Kingman, G. A., Pers, T. H., Baron, J., Rosenfeld, R. G., Hirschhorn, J. N., Harris, M. P., Hwa, V. Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein. J. Clin. Endocr. Metab. 97: E2140-E2151, 2012. Note: Electronic Article.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Ninein

Target: Ninein (NIN) (Ninein (GSK3B Interacting Protein) (NIN))

Andere Bezeichnung: NIN (NIN Produkte)

Hintergrund:

Synonyms: Endoglin, Cell surface MJ7/18 antigen, CD105, Eng, Edg,

Background: Ninein is a protein that in humans is encoded by the NIN gene. This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.

Molekulargewicht: 260 kDa

Gen-ID: 51199

UniProt: Q8N4C6

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom