TNNI3K Antikörper (AA 102-783)

Produktnummer ABIN7599644

Der Kaninchen Polyklonal Anti-TNNI3K-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, TNNI3K in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TNNI3K Antikörper (AA 102-783) (ABIN7599644)

Target: TNNI3K (TNNI3 Interacting Kinase (TNNI3K))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI3K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-TNNI3K Antikörper

Bindungsspezifität: AA 102-783

Verwendungszweck: Anti-TNNI3K Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TNNI3K Antibody Picoband® (ABIN7599644). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TNNI3K recombinant protein (Position: F102-Q783).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fan, L.-L., Huang, H., Jin, J.-Y., Li, J.-J., Chen, Y.-Q., Zhao, S.-P., Xiang, R. Whole exome sequencing identifies a novel mutation (c.333+2T-C) of TNNI3K in a Chinese family with dilated cardiomyopathy and cardiac conduction disease. Gene 648: 63-67, 2018. 2. Lai, Z.-F., Chen, Y.-Z., Feng, L.-P., Meng, X.-M., Ding, J.-F., Wang, L.-Y., Ye, J., Li, P., Cheng, X.-S., Kitamoto, Y., Monzen, K., Komuro, I., Sakaguchi, N., Kim-Mitsuyama, S. Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury. Am. J. Physiol. Heart Circ. Physiol. 295: H708-H716, 2008. Note: Erratum: Am. J. Physiol. Heart Circ. Physiol. 295: H1815 only, 2008. 3. Patterson, M., Barske, L., Van Handel, B., Rau, C. D., Gan, P., Sharma, A., Parikh, S., Denholtz, M., Huang, Y., Yamaguchi, Y., Shen, H., Allayee, H., Crump, J. G., Force, T. I., Lien, C.-L., Makita, T., Lusis, A. J., Kumar, S. R., Sucov, H. M. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genet. 49: 1346-1353, 2017.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TNNI3K

Target: TNNI3K (TNNI3 Interacting Kinase (TNNI3K))

Andere Bezeichnung: TNNI3K

Hintergrund:

Synonyms: Max dimerization protein 1, Max dimerizer 1, Protein MAD, MXD1, MAD

Background: TNNI3 interacting kinase is a protein that in humans is encoded by the TNNI3K gene. This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.

Molekulargewicht: 110 kDa

Gen-ID: 51086

UniProt: Q59H18