LYRM4 Antikörper (AA 1-91)

Produktnummer ABIN7599573

Produktdetails anti-LYRM4 Antikörper

Target: LYRM4 (LYR Motif Containing 4 (LYRM4))

Bindungsspezifität: AA 1-91

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LYRM4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Anti-LYRM4 Antibody Picoband®

Produktmerkmale: Anti-LYRM4 Antibody Picoband® (ABIN7599573). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LYRM4 recombinant protein (Position: M1-T91). Human LYRM4 shares 89% amino acid (aa) sequence identity with mouse LYRM4.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Adam, A. C., Bornhovd, C., Prokisch, H., Neupert, W., Hell, K. The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J. 25: 174-183, 2006. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 3/17/2010. 3. Lim, S. C., Friemel, M., Marum, J. E., Tucker, E. J., Bruno, D. L., Riley, L. G., Christodoulou, J., Kirk, E. P., Boneh, A., DeGennaro, C. M., Springer, M., Mootha, V. K., Rouault, T. A., Leimkuhler, S., Thorburn, D. R., Compton, A. G. Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. Hum. Molec. Genet. 22: 4460-4473, 2013.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu LYRM4

Target: LYRM4 (LYR Motif Containing 4 (LYRM4))

Andere Bezeichnung: LYRM4 (LYRM4 Produkte)

Hintergrund: The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis.

Molekulargewicht: 15 kDa

Gen-ID: 57128