NDUFA4 Antikörper (AA 1-81)

Produktnummer ABIN7599555

Produktdetails anti-NDUFA4 Antikörper

Target: NDUFA4 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 4 (NDUFA4))

Bindungsspezifität: AA 1-81

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: Anti-NDUFA4 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-NDUFA4 Antibody Picoband® (ABIN7599555). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NDUFA4 recombinant protein (Position: M1-F81).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Zhang, Y. , Ge, M. , Chen, Y. , Yang, Y. , Chen, W. , & Wu, D. , et al. (2022). Ndufa4 promotes cell proliferation by enhancing oxidative phosphorylation in pancreatic adenocarcinoma. Journal of Bioenergetics and Biomembranes, 54(5), 283-291. 2. Xu, W. , Lai, Y. , Pan, Y. , Tan, M. , Ma, Y. , & Sheng, H. , et al. M6a rna methylation-mediated ndufa4 promotes cell proliferation and metabolism in gastric cancer. Cell Death & Disease. 3. Ramzan, R. , Rhiel, A. , Weber, P. , Kadenbach, B. , & Vogt, S. . (2019). Reversible dimerization of cytochrome c oxidase regulates mitochondrial respiration. Mitochondrion, 49.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NDUFA4

Target: NDUFA4 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 4 (NDUFA4))

Andere Bezeichnung: NDUFA4 (NDUFA4 Produkte)

Hintergrund:

Synonyms: Interleukin 1 family member 10 ,Interleukin 1 family, member 10 (Predicted) ,Il1f10 ,Il1f10_predicted ,rCG_45898 ,

Tissue Specificity: Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.

Background: NDUFA4, mitochondrial complex associated is a protein that in humans is encoded by the NDUFA4 gene. The protein encoded by this gene belongs to the complex I 9 kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Molekulargewicht: 12 kDa

Gen-ID: 4697

UniProt: O00483