T-Box 18 Antikörper (AA 1-607)

Produktnummer ABIN7599494

Der Kaninchen Polyklonal Anti-T-Box 18-Antikörper wurde für ELISA, WB, IHC, IF und FACS validiert. Er ist geeignet, T-Box 18 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für T-Box 18 Antikörper (AA 1-607) (ABIN7599494)

Target: T-Box 18 (TBX18)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Box 18 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-T-Box 18 Antikörper

Bindungsspezifität: AA 1-607

Verwendungszweck: Anti-TBX18 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TBX18 Antibody Picoband® (ABIN7599494). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TBX18 recombinant protein (Position: M1-V607).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Airik, R., Bussen, M., Singh, M. K., Petry, M., Kispert, A. Tbx18 regulates the development of the ureteral mesenchyme. J. Clin. Invest. 116: 663-674, 2006. 2. Bussen, M, Petry, M., Schuster-Gossler, K., Leitges, M., Gossler, A., Kispert, A. The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 18: 1209-1221, 2004. 3. Cai, C.-L., Martin, J. C., Sun, Y., Cui, L., Wang, L., Ouyang, K., Yang, L., Bu, L., Liang, X., Zhang, X., Stallcup, W. B., Denton, C. P., McCulloch, A., Chen, J., Evans, S. M. A myocardial lineage derives from Tbx18 epicardial cells. Nature 454: 104-108, 2008.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu T-Box 18

Target: T-Box 18 (TBX18)

Andere Bezeichnung: TBX18

Hintergrund:

Synonyms: Aspartate--tRNA ligase, mitochondrial, Aspartyl-tRNA synthetase, AspRS, DARS2

Tissue Specificity: Detected in brain. Detected at very much lower levels in heart, lung, placenta and skeletal muscle. Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.

Background: This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors.

Molekulargewicht: 70 kDa

Gen-ID: 9096

UniProt: O95935

Pathways: Sensory Perception of Sound