KAT5 Antikörper (AA 1-56)

Produktnummer ABIN7599479

Der Kaninchen Polyklonal Anti-KAT5-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, KAT5 in Proben von Human zu detektieren.

Kurzübersicht für KAT5 Antikörper (AA 1-56) (ABIN7599479)

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-KAT5 Antikörper

Bindungsspezifität: AA 1-56

Verwendungszweck: Anti-Tip60/KAT5 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Tip60/KAT5 Antibody Picoband® (ABIN7599479). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Tip60/KAT5 recombinant protein (Position: M1-E56).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Baek, S. H., Ohgi, K. A., Rose, D. W., Koo, E. H., Glass, C. K., Rosenfeld, M. G. Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappa-B and beta-amyloid precursor protein. Cell 110: 55-67, 2002. 2. Bararia, D., Trivedi, A. K., Zada, A. A. P., Greif, P. A., Mulaw, M. A., Christopeit, M., Hiddemann, W., Bohlander, S. K., Behre, G. Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBP-alpha. Leukemia 22: 800-807, 2008. 3. Brady, M. E., Ozanne, D. M., Gaughan, L., Waite, I., Cook, S., Neal, D. E., Robson, C. N. Tip60 is a nuclear hormone receptor coactivator. J. Biol. Chem. 274: 17599-17604, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Andere Bezeichnung: KAT5

Hintergrund:

Synonyms: Retinal dehydrogenase 1, RALDH 1, RalDH1, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A, Aldehyde dehydrogenase, cytosolic, ALDH1A1, ALDC, ALDH1

Tissue Specificity: Strong expression found in normal gastric mucosa. Not detected in the small or large intestine nor in normal mammary gland.

Background: Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene. The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Molekulargewicht: 60 kDa

Gen-ID: 10524

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway