KLC1 Antikörper (AA 1-537)
Kurzübersicht für KLC1 Antikörper (AA 1-537) (ABIN7599468)
Target
Alle KLC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 1-537
-
Verwendungszweck
- Anti-KLC1 Antibody (monoclonal, 4F2D7)
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
-
Produktmerkmale
- Anti-KLC1 Antibody (monoclonal, 4F2D7) (ABIN7599468). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human KLC1 recombinant protein (Position: M1-D537).
-
Isotyp
- IgG2b
-
-
-
-
Applikationshinweise
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Konzentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- KLC1 (Kinesin Light Chain 1 (KLC1))
-
Andere Bezeichnung
- KLC1
-
Hintergrund
-
Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115
Background: Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.
-
Molekulargewicht
- 65 kDa
-
Gen-ID
- 3831
-
UniProt
- Q07866
-
Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
-