Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TRMT2B Antikörper (AA 1-504)

Dieses Anti-TRMT2B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRMT2B in WB, IHC, ELISA, FACS und IF. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7599456

Kurzübersicht für TRMT2B Antikörper (AA 1-504) (ABIN7599456)

Target

Alle TRMT2B Antikörper anzeigen
TRMT2B (tRNA Methyltransferase 2 Homolog B (TRMT2B))

Reaktivität

  • 18
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 16
  • 2
Kaninchen

Klonalität

  • 18
Polyklonal

Konjugat

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TRMT2B Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
  • Bindungsspezifität

    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-504

    Verwendungszweck

    Anti-TRMT2B Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TRMT2B Antibody Picoband® (ABIN7599456). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human TRMT2B recombinant protein (Position: M1-R504).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Minczuk, M. , & Powell, C. A. . Trmt2b is responsible for both trna and rrna m5u-methylation in human mitochondria. 2. Dai, W. , Li, A. , Yu, N. J. , Nguyen, T. , Leach, R. W. , & M Wühr, et al. Activity-based rna-modifying enzyme probing reveals dus3l-mediated dihydrouridylation. Nature chemical biology. 3. Daakour, S. , Hajingabo, L. J. , Kerselidou, D. , Devresse, A. , Kettmann, R. , & Simonis, N. , et al. (2016). Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals ext-1 tumor suppressor as a notch1 and fbwx7 common interactor. BMC Cancer.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    TRMT2B (tRNA Methyltransferase 2 Homolog B (TRMT2B))

    Andere Bezeichnung

    TRMT2B

    Hintergrund

    Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.

    Molekulargewicht

    47 kDa

    Gen-ID

    79979
Sie sind hier:
Chat with us!