MSL3 Antikörper (AA 1-498)

Produktnummer ABIN7599447

Dieses Anti-MSL3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MSL3 in WB und ELISA. Geeignet für Human.

Kurzübersicht für MSL3 Antikörper (AA 1-498) (ABIN7599447)

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MSL3 Antikörper

Bindungsspezifität: AA 1-498

Verwendungszweck: Anti-MSL3 Antibody Picoband®

Produktmerkmale: Anti-MSL3 Antibody Picoband® (ABIN7599447). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SLC7A7 recombinant protein (Position: M1-D498). Human SLC7A7 shares 90.8% and 91.6% amino acid (aa) sequence identity with mouse and rat SLC7A7, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Basilicata, M. F., Bruel, A.-L., Semplicio, G., Valsecchi, C. I. K., Aktas, T., Duffourd, Y., Rumpf, T., Morton, J., Bache, I., Szymanski, W. G., Gilissen, C., Vanakker, O., and 29 others. De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nature Genet. 50: 1442-1451, 2018. 2. Brunet, T., McWalter, K., Mayerhanser, K., Anbouba, G. M., Armstrong-Javors, A., Bader, I., Baugh, E., Begtrup, A., Bupp, C. P., Callewaert, B. L., Cereda, A., Cousin, M. A., and 49 others. Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder. Genet. Med. 23: 384-395, 2021. 3. Prakash, S. K., Van den Veyver, I. B., Franco, B., Volta, M., Ballabio, A., Zoghbi, H. Y. Characterization of a novel chromo domain gene in Xp22.3 with homology to Drosophila msl-3. Genomics 59: 77-84, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu MSL3

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Andere Bezeichnung: MSL3

Hintergrund: Y+L amino acid transporter 1 is a protein that in humans is encoded by the SLC7A7 gene. The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.

Molekulargewicht: 70 kDa

Gen-ID: 10943

UniProt: Q8N5Y2