RTN4IP1 Antikörper (AA 1-381)

Produktnummer ABIN7599334

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RTN4IP1 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RTN4IP1 Antikörper (AA 1-381) (ABIN7599334)

Target: RTN4IP1 (Reticulon 4 Interacting Protein 1 (RTN4IP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTN4IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-RTN4IP1 Antikörper

Bindungsspezifität: AA 1-381

Verwendungszweck: Anti-RTN4IP1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-RTN4IP1 Antibody Picoband® (ABIN7599334). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RTN4IP1 recombinant protein (Position: M1-K381).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Angebault, C., Guichet, P.-O., Talmat-Amar, Y., Charif, M., Gerber, S., Fares-Taie, L., Gueguen, N., Halloy, F., Moore, D., Amati-Bonneau, P., Manes, G., Hebrard, M., and 21 others. Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies. Am. J. Hum. Genet. 97: 754-760, 2015. Note: Erratum: Am. J. Hum. Genet. 97: 769 only, 2015. 2. Charif, M., Nasca, A., Thompson, K., Gerber, S., Makowski, C., Mazaheri, N., Bris, C., Goudenege, D., Legati, A., Maroofian, R., Shariati, G., Lamantea, E., and 30 others. Neurologic phenotypes associated with mutations in RTN4IP1 (OPA10) in children and young adults. JAMA Neurol. 75: 105-113, 2018. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/28/2010.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu RTN4IP1

Target: RTN4IP1 (Reticulon 4 Interacting Protein 1 (RTN4IP1))

Andere Bezeichnung: RTN4IP1

Hintergrund:

Synonyms: Follicular dendritic cell secreted peptide,FDC secreted protein,FDC-SP,FDCSP,C4orf7,UNQ733/PRO1419,

Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .

Background: This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 44 kDa

Gen-ID: 84816