MTCH2 Antikörper (AA 1-303)

Produktnummer ABIN7599247

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MTCH2 in WB, ELISA, IHC, IF, IP, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für MTCH2 Antikörper (AA 1-303) (ABIN7599247)

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTCH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-MTCH2 Antikörper

Bindungsspezifität: AA 1-303

Verwendungszweck: Anti-MTCH2 Antibody Picoband®

Produktmerkmale: Anti-MTCH2 Antibody Picoband® (ABIN7599247). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MTCH2 recombinant protein (Position: M1-I303). Human MTCH2 shares 93.7% amino acid (aa) sequence identity with mouse MTCH2.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
. Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Willer, C. J., Speliotes, E. K., Loos, R. J. F., Li, S., Lindgren, C. M., Heid, I. M., Berndt, S. I., Elliott, A. L., Jackson, A. U., Lamina, C., Lettre, G., Lim, N., and 134 others. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genet. 41: 25-34, 2009. 2. Yerushalmi, G. M., Leibowitz-Amit, R., Shaharabany, M., Tsarfaty, I. Met-HGF/SF signal transduction induces Mimp, a novel mitochondrial carrier homologue, which leads to mitochondrial depolarization. Neoplasia 4: 510-522, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu MTCH2

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Andere Bezeichnung: MTCH2

Hintergrund: Mitochondrial carrier homolog 2 also known as MTCH2 is a protein which in humans is encoded by the MTCH2 gene. This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons.

Molekulargewicht: 33 kDa

Gen-ID: 23788

UniProt: Q9Y6C9