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MTCH2 Antikörper (AA 1-303)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MTCH2 in WB, ELISA, IHC, IF, IP, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human und Ratte.
Produktnummer ABIN7599247

Kurzübersicht für MTCH2 Antikörper (AA 1-303) (ABIN7599247)

Target

Alle MTCH2 Antikörper anzeigen
MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Reaktivität

  • 30
  • 17
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Ratte

Wirt

  • 31
Kaninchen

Klonalität

  • 31
Polyklonal

Konjugat

  • 16
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MTCH2 Antikörper ist unkonjugiert

Applikation

  • 20
  • 14
  • 11
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-303

    Verwendungszweck

    Anti-MTCH2 Antibody Picoband®

    Produktmerkmale

    Anti-MTCH2 Antibody Picoband® (ABIN7599247). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human MTCH2 recombinant protein (Position: M1-I303). Human MTCH2 shares 93.7% amino acid (aa) sequence identity with mouse MTCH2.
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    . Immunoprecipitation, 0.5-2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Willer, C. J., Speliotes, E. K., Loos, R. J. F., Li, S., Lindgren, C. M., Heid, I. M., Berndt, S. I., Elliott, A. L., Jackson, A. U., Lamina, C., Lettre, G., Lim, N., and 134 others. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genet. 41: 25-34, 2009. 2. Yerushalmi, G. M., Leibowitz-Amit, R., Shaharabany, M., Tsarfaty, I. Met-HGF/SF signal transduction induces Mimp, a novel mitochondrial carrier homologue, which leads to mitochondrial depolarization. Neoplasia 4: 510-522, 2002.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    MTCH2 (Mitochondrial Carrier 2 (MTCH2))

    Andere Bezeichnung

    MTCH2

    Hintergrund

    Mitochondrial carrier homolog 2 also known as MTCH2 is a protein which in humans is encoded by the MTCH2 gene. This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons.

    Molekulargewicht

    33 kDa

    Gen-ID

    23788

    UniProt

    Q9Y6C9
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