TPI1 Antikörper (AA 1-286)

Produktnummer ABIN7599216

Dieses Anti-TPI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TPI1 in WB, ELISA und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TPI1 Antikörper (AA 1-286) (ABIN7599216)

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-TPI1 Antikörper

Bindungsspezifität: AA 1-286

Verwendungszweck: Anti-TPI1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TPI1 Antibody Picoband® (ABIN7599216). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TPI1 recombinant protein (Position: M1-Q286).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arya, R., Lalloz, M. R. A., Bellingham, A. J., Layton, D. M. Evidence for founder effect of the glu104-to-asp substitution and identification of new mutations in triosephosphate isomerase deficiency. Hum. Mutat. 10: 290-294, 1997. 2. Asakawa, J., Iida, S. Origin of human triosephosphate isomerase isozymes: further evidence for the single structural locus hypothesis with Japanese variants. Hum. Genet. 71: 22-26, 1985. 3. Asakawa, J., Satoh, C., Takahashi, N., Fujita, M., Kaneko, J., Goriki, K., Hazama, R., Kageoka, T. Electrophoretic variants of blood proteins in Japanese: III. Triosephosphate isomerase. Hum. Genet. 68: 185-188, 1984.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TPI1

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Andere Bezeichnung: TPI1

Hintergrund:

Synonyms: Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252, Tnfsf4, Ox40l, Txgp1l

Tissue Specificity: Macrophages, peripheral blood leukocytes, lung, spleen and liver.

Background: Triosephosphate isomerase is an enzyme that in humans is encoded by the TPI1 gene. This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 27 kDa

Gen-ID: 7167

UniProt: P60174

Pathways: Cell RedoxHomeostasis