PPP1R3B Antikörper (AA 1-285)

Produktnummer ABIN7599215

Der Kaninchen Polyklonal Anti-PPP1R3B-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, PPP1R3B in Proben von Human zu detektieren.

Kurzübersicht für PPP1R3B Antikörper (AA 1-285) (ABIN7599215)

Target: PPP1R3B (Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PPP1R3B Antikörper

Bindungsspezifität: AA 1-285

Verwendungszweck: Anti-PPP1R3B Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PPP1R3B Antibody Picoband® (ABIN7599215). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PPP1R3B recombinant protein (Position: M1-Y285).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Doherty, M. J., Moorhead, G., Morrice, N., Cohen, P., Cohen, P. T. W. Amino acid sequence and expression of hepatic glycogen-binding (G-L)-subunit of protein phosphatase-1. FEBS Lett. 375: 294-298, 1995. 2. Dunn, J. S., Mlynarski, W. M., Pezzoles, M. G., Borowiec, M., Powers, C., Krolewski, A. S., Doria, A. Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23. Ann. Hum. Genet. 70: 587-593, 2006. 3. Munro, S., Cuthbertson, D. J. R., Cunningham, J., Sales, M., Cohen, P. T. W. Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G-L of liver. Diabetes 51: 591-598, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PPP1R3B

Target: PPP1R3B (Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B))

Andere Bezeichnung: PPP1R3B

Hintergrund:

Synonyms: One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B

Tissue Specificity: Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.

Background: This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.

Molekulargewicht: 33 kDa

Gen-ID: 79660

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process