TRIM16 Antikörper (AA 1-218)

Produktnummer ABIN7599098

Der Kaninchen Polyklonal Anti-TRIM16-Antikörper wurde für ELISA, WB, IHC und FACS validiert. Er ist geeignet, TRIM16 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für TRIM16 Antikörper (AA 1-218) (ABIN7599098)

Target: TRIM16 (Tripartite Motif Containing 16 (TRIM16))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM16 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-TRIM16 Antikörper

Bindungsspezifität: AA 1-218

Verwendungszweck: Anti-TRIM16 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TRIM16 Antibody Picoband® (ABIN7599098). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TRIM16 recombinant protein (Position: M1-Q218).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Beer, H.-D., Munding, C., Dubois, N., Mamie, C., Hohl, D., Werner, S. The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation. J. Biol. Chem. 277: 20740-20749, 2002. 2. Liu, H.-L. C., Golder-Novoselsky, E., Seto, M. H., Webster, L., McClary, J., Zajchowski, D. A. The novel estrogen-responsive B box protein (EBBP) gene is tamoxifen regulated in cells expressing an estrogen receptor DNA-binding domain mutant. Molec. Endocr. 12: 1733-1748, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TRIM16

Target: TRIM16 (Tripartite Motif Containing 16 (TRIM16))

Andere Bezeichnung: TRIM16

Hintergrund:

Synonyms: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFP, MED20, TRFP,

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16 gene. The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy.

Molekulargewicht: 64 kDa

Gen-ID: 10626

UniProt: O95361

Pathways: Retinoic Acid Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Growth Factor Binding