ISOC2 Antikörper (AA 1-205)

Produktnummer ABIN7599080

Der Kaninchen Polyklonal anti-ISOC2 Antikörper wird verwendet zum Nachweis von ISOC2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, ICC und IF.

Kurzübersicht für ISOC2 Antikörper (AA 1-205) (ABIN7599080)

Target: ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISOC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-ISOC2 Antikörper

Bindungsspezifität: AA 1-205

Verwendungszweck: Anti-ISOC2 Antibody

Homologie: Human ISOC2 shares 84.2%,75% amino acid (aa) sequence identity with mouse,rat ISOC2,respectively.

Produktmerkmale: Anti-ISOC2 Antibody. Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ISOC2 recombinant protein (Position: M1-H205). Human ISOC2 shares 84.2% and 75% amino acid (aa) sequence identity with mouse and rat ISOC2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ISOC2

Target: ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

Andere Bezeichnung: ISOC2

Hintergrund:

Background: ISOC2 (isochorismatase domain-containing protein 2) is a 205 amino acid protein belonging to the isochorismatase family. Isochorismatase is an enzyme that catalyzes the chemical reaction of isochorismate and water to 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate. Localized to mitochondrion and cytoplasm, ISOC2 interacts with CDKN2A and localizes to the nucleus in the presence of it. ISOC2 is ubiquitously expressed, with highest levels found in uterus, stomach and urinary tract system. Over-expressed ISOC2 inhibits the expression of CDKN2A, suggesting that this novel gene may play a role during tumor development by interacting with CDKN2A. Three isoforms are produced by alternative splicing events.

Gene Full Name: isochorismatase domain containing 2

Molekulargewicht: 22 kDa

Gen-ID: 79763

UniProt: Q96AB3