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ISOC2 Antikörper (AA 1-205)

ISOC2 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7599080
  • Target Alle ISOC2 Antikörper anzeigen
    ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))
    Bindungsspezifität
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-205
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 14
    • 2
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ISOC2 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Verwendungszweck
    Anti-ISOC2 Antibody Picoband®
    Produktmerkmale
    Anti-ISOC2 Antibody Picoband® (ABIN7599080). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human ISOC2 recombinant protein (Position: M1-H205). Human ISOC2 shares 84.2% and 75% amino acid (aa) sequence identity with mouse and rat ISOC2, respectively.
    Top Product
    Discover our top product ISOC2 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Huang, X., Shi, Z., Wang, W., Bai, J., Chen, Z., Xu, J., Zhang, D., Fu, S. Identification and characterization of a novel protein ISOC2 that interacts with p16(INK4a). Biochem. Biophys. Res. Commun. 361: 287-293, 2007.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))
    Andere Bezeichnung
    ISOC2 (ISOC2 Produkte)
    Hintergrund
    ISOC2 (isochorismatase domain-containing protein 2) is a 205 amino acid protein belonging to the isochorismatase family. Isochorismatase is an enzyme that catalyzes the chemical reaction of isochorismate and water to 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate. Localized to mitochondrion and cytoplasm, ISOC2 interacts with CDKN2A and localizes to the nucleus in the presence of it. ISOC2 is ubiquitously expressed, with highest levels found in uterus, stomach and urinary tract system. Over-expressed ISOC2 inhibits the expression of CDKN2A, suggesting that this novel gene may play a role during tumor development by interacting with CDKN2A. Three isoforms are produced by alternative splicing events.
    Molekulargewicht
    22 kDa
    Gen-ID
    79763
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