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ISOC2 Antikörper (AA 1-205)

Der Kaninchen Polyklonal Anti-ISOC2-Antikörper wurde für WB, ELISA, ICC und IF validiert. Er ist geeignet, ISOC2 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7599080

Kurzübersicht für ISOC2 Antikörper (AA 1-205) (ABIN7599080)

Target

Alle ISOC2 Antikörper anzeigen
ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

Reaktivität

Human, Maus, Ratte

Wirt

  • 14
  • 2
Kaninchen

Klonalität

  • 15
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ISOC2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-205

    Verwendungszweck

    Anti-ISOC2 Antibody Picoband®

    Produktmerkmale

    Anti-ISOC2 Antibody Picoband® (ABIN7599080). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human ISOC2 recombinant protein (Position: M1-H205). Human ISOC2 shares 84.2% and 75% amino acid (aa) sequence identity with mouse and rat ISOC2, respectively.
  • Applikationshinweise

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Huang, X., Shi, Z., Wang, W., Bai, J., Chen, Z., Xu, J., Zhang, D., Fu, S. Identification and characterization of a novel protein ISOC2 that interacts with p16(INK4a). Biochem. Biophys. Res. Commun. 361: 287-293, 2007.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

    Andere Bezeichnung

    ISOC2

    Hintergrund

    ISOC2 (isochorismatase domain-containing protein 2) is a 205 amino acid protein belonging to the isochorismatase family. Isochorismatase is an enzyme that catalyzes the chemical reaction of isochorismate and water to 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate. Localized to mitochondrion and cytoplasm, ISOC2 interacts with CDKN2A and localizes to the nucleus in the presence of it. ISOC2 is ubiquitously expressed, with highest levels found in uterus, stomach and urinary tract system. Over-expressed ISOC2 inhibits the expression of CDKN2A, suggesting that this novel gene may play a role during tumor development by interacting with CDKN2A. Three isoforms are produced by alternative splicing events.

    Molekulargewicht

    22 kDa

    Gen-ID

    79763
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