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TSR2 Antikörper (AA 1-176)

TSR2 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7599035
  • Target Alle TSR2 Antikörper anzeigen
    TSR2 (TSR2, 20S rRNA Accumulation, Homolog (TSR2))
    Bindungsspezifität
    AA 1-176
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 7
    Kaninchen
    Klonalität
    • 7
    Polyklonal
    Konjugat
    • 3
    • 2
    • 1
    • 1
    Dieser TSR2 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-TSR2 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-TSR2 Antibody Picoband® (ABIN7599035). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human TSR2 recombinant protein (Position: M1-E176).
    Isotyp
    IgG
    Top Product
    Discover our top product TSR2 Primärantikörper
  • Applikationshinweise
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Gripp, K. W., Curry, C., Olney, A. H., Sandoval, C., Fisher, J., Chong, J. X.-L., UW Center for Mendelian Genomics, Pilchman, L., Sahraoui, R., Stabley, D. L., Sol-Church, K. Diamond-Blackfan anemia with mandibulofacial dystostosis (sic) is heterogeneous, including the novel DBA genes TSR2 and RPS28. Am. J. Med. Genet. 164A: 2240-2249, 2014. 2. Gripp, K. W., McDonald-McGinn, D. M., La Rossa, D., McGain, D., Federman, N., Vlachos, A., Glader, B. E., McKenzie, S. E., Lipton, J. M., Zackai, E. H. Bilateral microtia and cleft palate in cousins with Diamond-Blackfan anemia. Am. J. Med. Genet. 101: 268-274, 2001. 3. He, H., Zhu, D., Sun, J., Pei, R., Jia, S. The novel protein TSR2 inhibits the transcriptional activity of nuclear factor-kappa-B and induces apoptosis. Molec. Biol. (Mosk) 45: 451-457, 2011.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    TSR2 (TSR2, 20S rRNA Accumulation, Homolog (TSR2))
    Andere Bezeichnung
    TSR2 (TSR2 Produkte)
    Hintergrund

    Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

    Background: TSR2 ribosome maturation factor is a protein that in humans is encoded by the TSR2 gene. The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia.

    Molekulargewicht
    24-30 kDa
    Gen-ID
    90121
    UniProt
    Q969E8
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