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TSR2 Antikörper (AA 1-176)

Der Kaninchen Polyklonal Anti-TSR2-Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, TSR2 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7599035

Kurzübersicht für TSR2 Antikörper (AA 1-176) (ABIN7599035)

Target

Alle TSR2 Antikörper anzeigen
TSR2 (TSR2, 20S rRNA Accumulation, Homolog (TSR2))

Reaktivität

Human, Maus, Ratte

Wirt

  • 8
Kaninchen

Klonalität

  • 8
Polyklonal

Konjugat

  • 4
  • 2
  • 1
  • 1
Dieser TSR2 Antikörper ist unkonjugiert

Applikation

  • 6
  • 4
  • 3
  • 3
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    AA 1-176

    Verwendungszweck

    Anti-TSR2 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TSR2 Antibody Picoband® (ABIN7599035). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human TSR2 recombinant protein (Position: M1-E176).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Gripp, K. W., Curry, C., Olney, A. H., Sandoval, C., Fisher, J., Chong, J. X.-L., UW Center for Mendelian Genomics, Pilchman, L., Sahraoui, R., Stabley, D. L., Sol-Church, K. Diamond-Blackfan anemia with mandibulofacial dystostosis (sic) is heterogeneous, including the novel DBA genes TSR2 and RPS28. Am. J. Med. Genet. 164A: 2240-2249, 2014. 2. Gripp, K. W., McDonald-McGinn, D. M., La Rossa, D., McGain, D., Federman, N., Vlachos, A., Glader, B. E., McKenzie, S. E., Lipton, J. M., Zackai, E. H. Bilateral microtia and cleft palate in cousins with Diamond-Blackfan anemia. Am. J. Med. Genet. 101: 268-274, 2001. 3. He, H., Zhu, D., Sun, J., Pei, R., Jia, S. The novel protein TSR2 inhibits the transcriptional activity of nuclear factor-kappa-B and induces apoptosis. Molec. Biol. (Mosk) 45: 451-457, 2011.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    TSR2 (TSR2, 20S rRNA Accumulation, Homolog (TSR2))

    Andere Bezeichnung

    TSR2

    Hintergrund

    Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

    Background: TSR2 ribosome maturation factor is a protein that in humans is encoded by the TSR2 gene. The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia.

    Molekulargewicht

    24-30 kDa

    Gen-ID

    90121

    UniProt

    Q969E8
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