SNAIL Antikörper (AA 1-170)

Produktnummer ABIN7599028

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SNAIL in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SNAIL Antikörper (AA 1-170) (ABIN7599028)

Target: SNAIL (SNAI1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-SNAIL Antikörper

Bindungsspezifität: AA 1-170

Verwendungszweck: Anti-SNAIL/SNAI1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-SNAIL/SNAI1 Antibody Picoband® (ABIN7599028). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SNAIL/SNAI1 recombinant protein (Position: M1-K170).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: SNAI1 snail homolog 1 (Drosophila)". 2. Davidson NE, Sukumar S (September 2005). "Of Snail, mice, and women". Cancer Cell 8(3): 173-4.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: SNAI1

Hintergrund:

Synonyms: Emerin,EMD,EDMD, STA,

Tissue Specificity: Skeletal muscle, heart, colon, testis, ovary and pancreas.

Background: The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.

Molekulargewicht: 29 kDa

Gen-ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling