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SNRPC Antikörper (AA 1-159)

Der Kaninchen Polyklonal Anti-SNRPC-Antikörper wurde für WB, IHC, FACS, ICC, ELISA und IF validiert. Er ist geeignet, SNRPC in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7599016

Kurzübersicht für SNRPC Antikörper (AA 1-159) (ABIN7599016)

Target

Alle SNRPC Antikörper anzeigen
SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

Reaktivität

Human, Maus, Ratte

Wirt

  • 7
  • 1
Kaninchen

Klonalität

  • 7
  • 1
Polyklonal

Konjugat

  • 8
Dieser SNRPC Antikörper ist unkonjugiert

Applikation

  • 8
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 3
    • 2
    • 2
    • 1
    AA 1-159

    Verwendungszweck

    Anti-U1-C/SNRPC Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-U1-C/SNRPC Antibody Picoband® (ABIN7599016). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human U1-C/SNRPC recombinant protein (Position: M1-R159).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Du, H., Rosbash, M. The U1 snRNP protein U1C recognizes the 5-prime splice site in the absence of base pairing. Nature 419: 86-90, 2002. 2. Nelissen, R. L. H., Klein Gunnewiek, J. M. T., Lambermon, M. H. L., Van Venrooij, W. J. Cloning and characterization of two processed pseudogenes and the cDNA for the murine U1 snRNP-specific protein C. Gene 184: 273-278, 1997. 3. Sillekens, P. T. G., Beijer, R. P., Habets, W. J., van Venrooij, W. J. Human U1 snRNP-specific C protein: complete cDNA and protein sequences and identification of a multigene family in mammals. Nucleic Acids Res. 16: 8307-8321, 1988.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

    Andere Bezeichnung

    SNRPC

    Hintergrund

    Synonyms: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27

    Tissue Specificity: Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

    Background: U1 small nuclear ribonucleoprotein C is a protein that in humans is encoded by the SNRPC gene. This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.

    Molekulargewicht

    17 kDa

    Gen-ID

    6631

    UniProt

    P09234

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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