SSBP1 Antikörper (AA 1-148)

Produktnummer ABIN7599002

Dieses Anti-SSBP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SSBP1 in WB, ELISA, IHC, IF, ICC und FACS. Geeignet für Human.

Kurzübersicht für SSBP1 Antikörper (AA 1-148) (ABIN7599002)

Target: SSBP1 (Single-Stranded DNA Binding Protein 1 (SSBP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-SSBP1 Antikörper

Bindungsspezifität: AA 1-148

Verwendungszweck: Anti-SSBP1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SSBP1 Antibody Picoband® (ABIN7599002). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SSBP1 recombinant protein (Position: M1-E148).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bogenhagen, D. F., Rousseau, D., Burke, S. The layered structure of human mitochondrial DNA nucleoids. J. Biol. Chem. 283: 3665-3675, 2008. 2. Del Dotto, V., Ullah, F., Di Meo, I., Magini, P., Gusic, M., Maresca, A., Caporali, L., Palombo, F., Tagliavini, F., Baugh, E. H., Macao, B., Szilagyi, Z., and 35 others. SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. J. Clin. Invest. 130: 108-125, 2020. 3. Huang, J., Gong, Z., Ghosal, G., Chen, J. SOSS complexes participate in the maintenance of genomic stability. Molec. Cell 35: 384-393, 2009.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SSBP1

Target: SSBP1 (Single-Stranded DNA Binding Protein 1 (SSBP1))

Andere Bezeichnung: SSBP1

Hintergrund:

Synonyms: Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25,

Tissue Specificity: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen .

Background: Single-stranded DNA-binding protein, mitochondrial is a protein that in humans is encoded by the SSBP1 gene. SSBP1 is a housekeeping gene involved in mitochondrial biogenesis. It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability.

Molekulargewicht: 16 kDa

Gen-ID: 6742

UniProt: Q04837

Pathways: Chromatin Binding