Glutaredoxin 1 Antikörper (AA 1-106)
Kurzübersicht für Glutaredoxin 1 Antikörper (AA 1-106) (ABIN7598941)
Target
Alle Glutaredoxin 1 (GRX1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-106
-
Verwendungszweck
- Anti-Glutaredoxin 1/GLRX Antibody
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
-
Produktmerkmale
- Anti-Glutaredoxin 1/GLRX Antibody (ABIN7598941). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human Glutaredoxin 1/GLRX recombinant protein (Position: M1-Q106).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Konzentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Glutaredoxin 1 (GRX1)
-
Andere Bezeichnung
- GLRX
-
Hintergrund
-
Synonyms: Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, Gc
Background: Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
-
Molekulargewicht
- 12 kDa
-
Gen-ID
- 2745
-
UniProt
- P35754
-
Pathways
- Cell RedoxHomeostasis
Target
-