OGDHL Antikörper (AA 1-1010)

Produktnummer ABIN7598933

Dieses Anti-OGDHL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von OGDHL in WB, ELISA, ICC, IF und FACS. Geeignet für Human, Ratte und Maus.

Kurzübersicht für OGDHL Antikörper (AA 1-1010) (ABIN7598933)

Target: OGDHL (Oxoglutarate Dehydrogenase-Like (OGDHL))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OGDHL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-OGDHL Antikörper

Bindungsspezifität: AA 1-1010

Verwendungszweck: Anti-OGDHL Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-OGDHL Antibody Picoband® (ABIN7598933). Tested in ELISA, IF, ICC, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human OGDHL recombinant protein (Position: M1-F1010).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bunik, V. I., Degtyarev, D. Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins. Proteins 71: 874-890, 2008. 2. Nagase, T., Ishikawa, K., Kikuno, R., Hirosawa, M., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 337-345, 1999. 3. Sen, T., Sen, N., Noordhuis, M. G., Ravi, R., Wu, T.-C., Ha, P. K., Sidransky, D., Hoque, M. O. OGDHL is a modifier of AKT-dependent signaling and NF-kappaB function. PLoS One 7: e48770, 2012. Note: Electronic Article.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu OGDHL

Target: OGDHL (Oxoglutarate Dehydrogenase-Like (OGDHL))

Andere Bezeichnung: OGDHL

Hintergrund:

Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3

Tissue Specificity: Brain. Expression restricted to astrocytes.

Background: The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells.

Molekulargewicht: 100 kDa

Gen-ID: 55753