ACAT1 Antikörper (AA 34-427)
Kurzübersicht für ACAT1 Antikörper (AA 34-427) (ABIN7596086)
Target
Alle ACAT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 34-427
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Verwendungszweck
- Human ACAT1 antibody
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Aufreinigung
- protein-A affinity chromatography
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Immunogen
- Recombinant human ACAT1 (34-427aa) purified from E. coli
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))
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Andere Bezeichnung
- ACAT1
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Hintergrund
- ACAT1 (acetyl-Coenzyme A acetyltransferase 1) is a 417 amino acid protein. ACAT1 is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. ACAT1 and ACAT2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction. Defects in ACAT1 are a cause of 3-ketothiolase deficiency. 3-ketothiolase deficiency is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded.
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NCBI Accession
- NP_000010
Target
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