LSM2 Antikörper (AA 1-95)

Produktnummer ABIN7596084

Produktdetails anti-LSM2 Antikörper

Target: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Bindungsspezifität: AA 1-95

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LSM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Human LSM2 antibody

Aufreinigung: protein-A affinity chromatography

Immunogen: Recombinant human LSm2 (1-95aa) purified from E. coli

Klon: AT1G7

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu LSM2

Target: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Andere Bezeichnung: LSM2 (LSM2 Produkte)

Hintergrund: LSM2 is a member of the LSm family of RNA-binding proteins. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic complex which is thought to be involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2 complex, which is involved in splicing of nuclear mRNAs. LSM2 associates with multiple snRNP complexes containing the U6 snRNA It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.

NCBI Accession: NP_067000

Pathways: Ribonucleoprotein Complex Subunit Organization