MEMO1 Antikörper (AA 1-297)

Produktnummer ABIN7596069

Produktdetails anti-MEMO1 Antikörper

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Bindungsspezifität: AA 1-297

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MEMO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Verwendungszweck: Human MEMO1 antibody

Aufreinigung: protein-A affinity chromatography

Immunogen: Recombinant human MEMO1 (1-297aa) purified from E. coli

Klon: AT1E9

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Andere Bezeichnung: MEMO1 (MEMO1 Produkte)

Hintergrund: MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.

NCBI Accession: NP_057039