GARS Antikörper (AA 43-289)

Produktnummer ABIN7596061

Der Maus Monoklonal Anti-GARS-Antikörper wurde für WB, IF, ELISA und ICC validiert. Er ist geeignet, GARS in Proben von Human zu detektieren.

Kurzübersicht für GARS Antikörper (AA 43-289) (ABIN7596061)

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Klon: AT4E10

Produktdetails anti-GARS Antikörper

Bindungsspezifität: AA 43-289

Verwendungszweck: Human GARS antibody

Aufreinigung: protein-A affinity chromatography

Immunogen: Recombinant human GARS (43-289aa) purified from E. coli

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu GARS

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Andere Bezeichnung: GARS

Hintergrund: GARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetase that charge tRNAswith their cognate amino acids. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Toothdisease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness,atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also thecause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distalsensory involvement is less severe in HMN5 patients.

NCBI Accession: NP_002038

Pathways: Ribonucleoside Biosynthetic Process