NCR1 Antikörper (AA 22-255)

Produktnummer ABIN7596031

Der Maus Monoklonal Anti-NCR1-Antikörper wurde für FACS und ELISA validiert. Er ist geeignet, NCR1 in Proben von Human zu detektieren.

Kurzübersicht für NCR1 Antikörper (AA 22-255) (ABIN7596031)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Klon: N1D9

Produktdetails anti-NCR1 Antikörper

Bindungsspezifität: AA 22-255

Verwendungszweck: Human NKp46/NCR1 antibody

Aufreinigung: protein-A affinity chromatography

Immunogen: Recombinant human Nkp46/NCR1 (22-255aa) purified from E. coli.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: NKp46/NCR1

Hintergrund: A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appearto be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

NCBI Accession: NP_004820

Pathways: Regulation of Leukocyte Mediated Immunity