FGF12 Antikörper (AA 1-243) (FL650)
Kurzübersicht für FGF12 Antikörper (AA 1-243) (FL650) (ABIN7595802)
Target
Alle FGF12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-243
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Verwendungszweck
- Anti-FGF12/FHF1 Antibody FL650 Conjugate
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Spezifität
- Recognizes FGF12b/FHF1bNo off-targets reported for FGF11/FHF3, FGF13/FHF2 or FGF14/FHF4
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
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Description: Our Anti-FGF12/FHF1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N94/17. It detects human, mouse, and rat FGF12/FHF1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our FGF12/FHF1 mouse monoclonal primary antibody from hybridoma clone N94/17. It is great in IHC, ICC and is purified by Protein A chromatography.
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Aufreinigung
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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Reinheit
- > 90 % specific antibody
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Immunogen
- Fusion protein amino acids 1-243 (full-length) of human FGF12a (accession number P61328) produced recombinantly in E. Coli
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS with 0.09 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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Haltbarkeit
- 12 months
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- FGF12 (Fibroblast Growth Factor 12 (FGF12))
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Andere Bezeichnung
- FHF1
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Hintergrund
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Synonyms: Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor)
Target Description: Fibroblast growth factor 12, FHF1 or FGF12 is encoded by the gene FGF12. FHF1 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF12 has been found to be expressed in the brain, eye and testis. Diseases associated with FGF12 include Early Infantile Epileptic Encephalopathy, Ebstein anomaly and Autosomal Dominant Deafness.
Gene Name Alternatives: FGF12 FGF12B FHF1
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Molekulargewicht
- 27 kDa
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Pathways
- Negative Regulation of Transporter Activity
Target
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