ANK2 Antikörper (AA 203-496) (FL594)
Kurzübersicht für ANK2 Antikörper (AA 203-496) (FL594) (ABIN7595701)
Target
Alle ANK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 203-496
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Verwendungszweck
- Anti-Ankyrin-B Antibody FL594 Conjugate
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Spezifität
- No off-targets reported
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Kreuzreaktivität
- Meerschweinchen, Human, Maus, Ratte
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Produktmerkmale
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Description: Our Anti-Ankyrin-B mouse monoclonal primary antibody is produced in-house from hybridoma clone N105/17. It detects human, mouse, and rat Ankyrin-B, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our Ankyrin-B mouse monoclonal primary antibody from hybridoma clone N105/17. It is great in IHC, ICC and is purified by Protein A chromatography.
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Aufreinigung
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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Reinheit
- > 90 % specific antibody
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Immunogen
- Fusion protein amino acids 203-496 of human Ankyrin-B (accession number Q01484) produced recombinantly in E. Coli
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS with 0.09 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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Haltbarkeit
- 12 months
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- ANK2 (Ankyrin 2, Neuronal (ANK2))
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Andere Bezeichnung
- Ankyrin-B
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Hintergrund
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Synonyms: Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
Target Description: Ankyrin-2 or -Ankyrin-B is encoded by the gene ANK2. Ankyrin B is a scaffold protein that functions to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin B is expressed in brain and muscle. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome.
Gene Name Alternatives: ANK2 ANKB
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Molekulargewicht
- <200 kDa
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Pathways
- Cell-Cell Junction Organization
Target
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