NFASC Antikörper (Intracellular) (FL490)

Produktnummer ABIN7595517

Der Maus Monoklonal Anti-NFASC-Antikörper wurde für IHC und ICC validiert. Er ist geeignet, NFASC in Proben von Ratte zu detektieren.

Kurzübersicht für NFASC Antikörper (Intracellular) (FL490) (ABIN7595517)

Target: NFASC (Neurofascin (NFASC))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NFASC Antikörper ist konjugiert mit FL490

Applikation: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: L11A-41

Produktdetails anti-NFASC Antikörper (FL490)

Bindungsspezifität: Intracellular

Verwendungszweck: Anti-Pan-Neurofascin Antibody FL490 Conjugate

Spezifität: No off-targets reported

Kreuzreaktivität: Human, Ratte

Produktmerkmale:

Description: Our Anti-Pan-Neurofascin mouse monoclonal primary antibody is produced in-house from hybridoma clone L11A/41. It detects human and rat Pan-Neurofascin, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Pan-Neurofascin mouse monoclonal primary antibody from hybridoma clone L11A/41. It is great in IHC, ICC and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Reinheit: > 90 % specific antibody

Immunogen: Fusion protein 1066-1174 (intracellular domain common to NF-155 and NF-186) of rat NF-155 (accession number AAL27854) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 12 months

Details zu NFASC

Target: NFASC (Neurofascin (NFASC))

Andere Bezeichnung: Neurofascin

Hintergrund:

Synonyms: Neurofascin NF-155 NF-186

Target Description: Neurofascin is encoded by the gene NFASC. Two major isoforms of NeuroFascin are expressed as a result of alternative splicing, NF186 and NF155. These proteins are expressed in the central nervous system. In brain, NF186 is expressed at Nodes of Ranvier andNF155 is expressed in unmyelinated axons. Neuofascin plays a role in cell adhesion and is thought to be involved in processes such as neurite extension, synaptogenesis and myelination. Diseases associated with this gene include Demyelinating Polyneuropathy.

Gene Name Alternatives: Nfasc

Molekulargewicht: 155, 186 kDa (plus additional bands on immunoblot)

Pathways: Cell-Cell Junction Organization