ANK2 Antikörper (AA 203-496) (FL490)

Produktnummer ABIN7595437

Dieses Anti-ANK2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ANK2 in IHC und ICC. Geeignet für Human.

Kurzübersicht für ANK2 Antikörper (AA 203-496) (FL490) (ABIN7595437)

Target: ANK2 (Ankyrin 2, Neuronal (ANK2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ANK2 Antikörper ist konjugiert mit FL490

Applikation: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: N105-17

Produktdetails anti-ANK2 Antikörper (FL490)

Bindungsspezifität: AA 203-496

Verwendungszweck: Anti-Ankyrin-B Antibody FL490 Conjugate

Spezifität: No off-targets reported

Kreuzreaktivität: Meerschweinchen, Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-Ankyrin-B mouse monoclonal primary antibody is produced in-house from hybridoma clone N105/17. It detects human, mouse, and rat Ankyrin-B, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Ankyrin-B mouse monoclonal primary antibody from hybridoma clone N105/17. It is great in IHC, ICC and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Reinheit: > 90 % specific antibody

Immunogen: Fusion protein amino acids 203-496 of human Ankyrin-B (accession number Q01484) produced recombinantly in E. Coli

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 12 months

Details zu ANK2

Target: ANK2 (Ankyrin 2, Neuronal (ANK2))

Andere Bezeichnung: Ankyrin-B

Hintergrund:

Synonyms: Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)

Target Description: Ankyrin-2 or -Ankyrin-B is encoded by the gene ANK2. Ankyrin B is a scaffold protein that functions to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin B is expressed in brain and muscle. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome.

Gene Name Alternatives: ANK2 ANKB

Molekulargewicht: <200 kDa

Pathways: Cell-Cell Junction Organization