Fc epsilon RI/FCER1A Antikörper

Produktnummer ABIN7595383

Der Maus Monoklonal anti-Fc epsilon RI/FCER1A Antikörper (Klon AER-37 [CRA1]) (ABIN7595383) detektiert spezifisch Fc epsilon RI/FCER1A in FACS, ICC und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Non-Human Primate.

Kurzübersicht für Fc epsilon RI/FCER1A Antikörper (ABIN7595383)

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fc epsilon RI/FCER1A Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: AER-37 [CRA1]

Produktdetails anti-Fc epsilon RI/FCER1A Antikörper

Verwendungszweck: Anti-Hu Fc epsilon RIa Purified

Produktmerkmale: The mouse monoclonal antibody AER-37 [CRA1] recognizes an extracellular epitope of the high-affinity IgE receptor I alpha subunit (Fc epsilon RIa).

Aufreinigung: Purified by protein-A affinity chromatography.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu Fc epsilon RI/FCER1A

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Andere Bezeichnung: Fc epsilon RIa

Hintergrund: Folate receptor beta,FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.,Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1

Gen-ID: 2205

UniProt: P12319

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process