ITGA4 Antikörper

Produktnummer ABIN7595333

Dieser Maus Monoklonal Antikörper detektiert spezifisch ITGA4 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ITGA4 Antikörper (ABIN7595333)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: OSX14

Produktdetails anti-ITGA4 Antikörper

Verwendungszweck: Mouse monoclonal to Integrin alpha 4: OSX14 clone

Spezifität: Specific for Integrin α,4

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: Integrin alpha 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC. A dilution of 1 : 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Andere Bezeichnung: Integrin alpha 4

Hintergrund: FUNCTION: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.

Pathways: Integrin Complex