NOS1 Antikörper

Produktnummer ABIN7595322

Der Huhn Polyklonal Anti-NOS1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, NOS1 in Proben von Human zu detektieren.

Kurzübersicht für NOS1 Antikörper (ABIN7595322)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser NOS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NOS1 Antikörper

Verwendungszweck: Chicken antibody to nNOS

Spezifität: Specific for nNOS

Kreuzreaktivität: Human, Marmoset, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: Purified IgY

Immunogen: A synthetic peptide from human nNOS conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 96% identity with rat's sequence.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: IHC WB. A dilution of 1: 500 is recommended. The optimal dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term.

Haltbarkeit: 12 months

Details zu NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Andere Bezeichnung: nNOS

Hintergrund: FUNCTION: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. SUBCELLULAR LOCATION: Cell membrane sarcolemma, Peripheral membrane protein. Cell projection dendritic spine. Note=In skeletal muscle it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons enriched in dendritic spines. TISSUE SPECIFICITY: Isoform N-NOS-1 is expressed in brain and colorectum. Found in the Auerbach's plexus of the enteric nervous system. Isoform PNNOS is expressed in the penis urethra prostate and skeletal muscle and coexists with the cerebellar nnos in the pelvic plexus bladder and liver and is detectable in the cerebellum.

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction