GOT1 Antikörper

Produktnummer ABIN7595314

Dieses Anti-GOT1-Antikörper ist ein Meerschweinchen Polyklonal-Antikörper zur Detektion von GOT1 in WB, IHC und IHC (p). Geeignet für Ratte.

Kurzübersicht für GOT1 Antikörper (ABIN7595314)

Target: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Reaktivität: Ratte

Wirt: Meerschweinchen

Klonalität: Polyklonal

Konjugat: Dieser GOT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GOT1 Antikörper

Verwendungszweck: Guinea pig antibody to Aspartate Aminotransferase (AATC)

Spezifität: Specific for AATC

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Whole serum

Immunogen: A synthetic peptide from rat AATC conjugated to blue carrier protein was used as the antigen.

Anwendungsinformationen

Applikationshinweise: IHC WB. A dilution of 1: 500 is recommended for IHC-P,WB. The optimal dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu GOT1

Target: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Andere Bezeichnung: Aspartate Aminotransferase

Hintergrund: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate regulates levels of mercaptopyruvate an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Pathways: Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process