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NPTXR Antikörper (Extracellular) (FITC)

Der Kaninchen Polyklonal Anti-NPTXR-Antikörper wurde für FACS und LCI validiert. Er ist geeignet, NPTXR in Proben von Maus zu detektieren.
Produktnummer ABIN7582052

Kurzübersicht für NPTXR Antikörper (Extracellular) (FITC) (ABIN7582052)

Target

Alle NPTXR Antikörper anzeigen
NPTXR (Neuronal Pentraxin Receptor (NPTXR))

Reaktivität

  • 16
  • 5
  • 4
Maus

Wirt

  • 14
  • 2
  • 2
Kaninchen

Klonalität

  • 18
  • 1
Polyklonal

Konjugat

  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser NPTXR Antikörper ist konjugiert mit FITC

Applikation

  • 19
  • 14
  • 14
  • 2
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS), Live Cell Imaging (LCI)
  • Bindungsspezifität

    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-176, Extracellular

    Verwendungszweck

    A Rabbit Polyclonal Antibody to Neuronal Pentraxin Receptor (NPTXR) (extracellular) conjugated to the fluorescent dye FITC

    Sequenz

    (C)RGLQDAGPRR DTMAD

    Spezifität

    Extracellular, C-terminus

    Homologie

    Rat - identical, human - 14 out of 15 amino acid residues identical

    Produktmerkmale

    Anti-Neuronal Pentraxin Receptor (NPTXR) (extracellular) Antibody (ABIN7043370, ABIN7044746 and ABIN7044747) is a highly specific antibody directed against an extracellular epitope of the mouse NPTXR. The antibody can be used in western blot and immunohistochemistry. It has been designed to recognize NPTXR from mouse, rat and human samples. Anti-Neuronal Pentraxin Receptor (NPTXR) (extracellular)-FITC Antibody (ABIN7043370, ABIN7044746 and ABIN7044747-F) is directly conjugated to fluorescein isothiocyanate (FITC) fluorophore. This conjugated antibody has been developed to be used in immunofluorescent applications such as direct flow cytometry and live cell imaging.

    Aufreinigung

    Affinity purified on immobilized antigen.

    Immunogen

    (C)RGLQDAGPRRDTMAD, corresponding to amino acid residues 162 - 176 of mouse NPTXR 

    Isotyp

    IgG
  • Applikationshinweise

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Kommentare

    Negative Control: (ABIN7582044)

    Blocking Peptide: (ABIN7236082)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    15 μL or 50 μL double distilled water (DDW), depending on the sample size.

    Konzentration

    1 mg/mL

    Buffer

    PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • Target

    NPTXR (Neuronal Pentraxin Receptor (NPTXR))

    Andere Bezeichnung

    NPTXR

    Hintergrund

    NPR, NPTXR,Neuronal Pentraxin Receptor (NPTXR) belongs to the Pentraxin superfamily of proteins (NP) that is characterized by a pentraxin domain at the C-terminal end. It is the only pentraxin family member anchored to the cell membrane by a putative N-terminal transmembrane domain, as opposed to the other two family members, Neuronal Pentraxin1 (NP1) and Neuronal Pentraxin 2 (NP2) that are secreted proteins. NPs can form homo pentamers and hetero pentamers via their pentraxin domains 1.NPTXR was first identified as the receptor for the snake venom toxin taipoxin and was later found to bind to AMPARs at excitatory synapses and play important, roles in the activity-dependent regulation of neural circuits via this binding activity 1.Lately, the levels of NPTXR protein in cerebrospinal fluid has been identified as a novel potential biomarker of Alzheimer's disease progression and could have important utility in assessing treatment success in clinical trials 2. In addition, NPTXR was identified as a molecule required for gastric cancer metastasis 3.

    Gen-ID

    73340

    UniProt

    Q99J85
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