KISS1R Antikörper (Extracellular) (FITC)

Produktnummer ABIN7582049

Der Kaninchen Polyklonal Anti-KISS1R-Antikörper wurde für FACS und LCI validiert. Er ist geeignet, KISS1R in Proben von Human zu detektieren.

Kurzübersicht für KISS1R Antikörper (Extracellular) (FITC) (ABIN7582049)

Target: KISS1R (KISS1 Receptor (KISS1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1R Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Live Cell Imaging (LCI)

Produktdetails anti-KISS1R Antikörper (FITC)

Bindungsspezifität: AA 292-305, Extracellular

Verwendungszweck: A Rabbit Polyclonal Antibody to KISS1 Receptor (GPR54) (extracellular) conjugated to the fluorescent dye FITC

Sequenz: (C)GSWHPRSYAA YALK

Spezifität: 3rd extracellular loop

Homologie: Rat - 13 out of 14 amino acid residues identical,Mouse - 12 out of 14 amino acid residues identical

Produktmerkmale: Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549) is a highly specific antibody directed against an epitope of human KISS1 receptor. The antibody can be used in western blot, immunohistochemistry and flow cytometry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples. Anti-KISS1 Receptor (GPR54) (extracellular)-FITC Antibody (ABIN7043294, ABIN7044548 and ABIN7044549-F) is directly conjugated to fluorescein isothiocyanate (FITC) fluorophore. This conjugated antibody has been developed to be used in immunofluorescent applications such as direct flow cytometry and live cell imaging.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: N/A

Kommentare:

Negative Control: (ABIN7582044)

Blocking Peptide: (ABIN7235833)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 50 μL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Andere Bezeichnung: KISS1R

Hintergrund: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12, G-Protein Coupled Receptor 54,The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3

Gen-ID: 84634

UniProt: Q969F8