Rekombinanter CRP Antikörper

Produktnummer ABIN7581768

Der Maus Monoklonal Anti-CRP-Antikörper wurde für ELISA validiert. Er ist geeignet, CRP in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter CRP Antikörper (ABIN7581768)

Target: CRP (C-Reactive Protein (CRP))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CRP Antikörper ist unkonjugiert

Applikation: ELISA

Güteklasse: Animal-Free

Klon: AB469-1-A05

Produktdetails anti-CRP Antikörper

Expressionssystem: Phage display

Verwendungszweck: Mouse Anti- human C-reactive protein (CRP)

Spezifität: This is an antibody developed by antibody phage display technology using a human naive antibody gene library and human C-reactive protein (CRP) antigen. For this antibody both the heavy and light chains are cloned and expressed, generating full-length antibodies.

Produktmerkmale: This antibody can be detected with anti-mouse Fc secondary antibodies.

Aufreinigung: Protein A purification

Immunogen: No immunization, animal-free antibody development. Antigen: human C-reactive protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1-12 μg/mL as coating antibody 0.5-5 μg/mL as detection antibody Optimal working dilution should be determined by the investigator

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4,

Lagerung: -20 °C

Details zu CRP

Target: CRP (C-Reactive Protein (CRP))

Andere Bezeichnung: C-reactive Protein

Hintergrund: C-reactive protein (CRP) is an important acute-phase protein produced by the liver in response to inflammation, primarily triggered by the cytokine interleukin-6 (IL-6). Structurally, CRP is a pentamer composed of five identical subunits, which enables it to bind to phosphocholine on the surfaces of dead or dying cells and certain bacteria. This binding facilitates the activation of the complement system and enhances phagocytosis, playing a crucial role in the innate immune response. Clinically, elevated CRP levels in the blood serve as a non-specific marker of inflammation, making it useful for diagnosing and monitoring conditions such as infections, autoimmune disorders, and inflammatory diseases like rheumatoid arthritis and inflammatory bowel disease (IBD). High-sensitivity CRP (hs-CRP) tests are also utilized to assess the risk of cardiovascular diseases, including heart attacks and strokes, by detecting low levels of chronic inflammation. In summary, C-reactive protein is a key indicator of inflammation and immune system activity, widely used in medical diagnostics to evaluate and monitor various inflammatory and infectious conditions.

Molekulargewicht: 115 kDa

Gen-ID: 1401

NCBI Accession: NG_013007

UniProt: P02741

Pathways: Carbohydrate Homeostasis